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1.
Surgery ; 174(4): 1041-1049, 2023 10.
Artículo en Inglés | MEDLINE | ID: mdl-37481423

RESUMEN

BACKGROUND: Intertrochanteric fracture in the geriatric population is associated with poor prognosis, which may be attributed to consistent stress and the systemic inflammatory response. Dexamethasone is an exogenous glucocorticoid commonly used in clinical practice for broad anti-inflammatory action. The purpose is to investigate whether a single preoperative low-dose dexamethasone can improve the in-hospital prognosis in geriatric intertrochanteric fracture patients undergoing internal fixation surgery. METHODS: Between June 2020 and October 2022, 219 eligible patients with intertrochanteric fractures were in this study. After meeting the inclusion and exclusion criteria, 160 patients were randomly allocated to the dexamethasone or placebo groups (80 patients who are geriatric with an intertrochanteric fracture in each group). The patients in the dexamethasone group received 10 mg (2 mL) of dexamethasone intravenously, whereas the patients in the placebo group received 2 mL of saline intravenously within 30 minutes before being sent to the operating room. The efficacy-related outcomes (the first bed-chair transfer ability, in-hospital mortality, and length of stay) and safety-related outcomes (infection events and hyperglycemia) were collected for analysis. RESULTS: There were no significant differences in the baseline characteristics between the 2 groups. The dexamethasone group had a significantly higher rate of the first bed-chair transfer than the placebo group (65.0% [52/80] vs 48.8% [39/80], relative risk = 1.46, 95% confidence interval = 1.02 to 2.11; P = .038). One patient in the dexamethasone group and 7 patients in the placebo group died during hospitalization (1.3% [1/80] vs 8.8% [7/80], relative risk = 0.92, 95% confidence interval = 0.86 to 0.99; P = .07). No differences were found in the length of stay, infections, and hyperglycemia between the 2 groups. CONCLUSION: A single preoperative low-dose of dexamethasone can improve the in-hospital prognosis (increase the ability of the first bed-chair transfer and potentially decrease the in-hospital mortality) in geriatric intertrochanteric fracture patients after internal fixation surgery.


Asunto(s)
Fracturas de Cadera , Hiperglucemia , Humanos , Anciano , Pronóstico , Hospitales , Fracturas de Cadera/cirugía , Hiperglucemia/etiología , Hiperglucemia/prevención & control , Dexametasona
2.
J Orthop Surg Res ; 18(1): 441, 2023 Jun 19.
Artículo en Inglés | MEDLINE | ID: mdl-37337260

RESUMEN

OBJECTIVE: Postoperative delirium (POD) is a common complication along with poor prognosis in geriatric intertrochanteric fracture (ITF) patients. However, the prevention and treatment of POD remain unclear. Previous studies have confirmed that POD is essentially a consequence of neuro-inflammatory responses. Dexamethasone is a glucocorticoid with comprehensive anti-inflammatory effects, while a high dose of dexamethasone correlates with many side effects or even adverse consequences. Thus, this prospective study aims to discuss whether a single preoperative low-dose dexamethasone can reduce the impact of POD on geriatric ITF patients with internal fixation surgery. METHODS: Between June 2020 and October 2022, there were 219 consecutive ITF patients assessed in our department. Of the 219 ITF patients, 160 cases who met the inclusion and exclusion criteria were finally enrolled and randomly allocated to the dexamethasone group and the placebo group (80 geriatric ITF patients in each group) in this prospective study. The patients in the dexamethasone group received intravenous 10 mg (2 ml) dexamethasone while the patients in the placebo group received intravenous 2 ml saline in 30 min before being sent to the operating room, respectively. The baseline characteristics, surgical information, incidence and severity of POD as the efficacy-related outcomes, and infection events and hyperglycemia as safety-related outcomes (adverse events), were collected and analyzed between the two groups. The severity of POD was evaluated by Memorial Delirium Assessment Scale (MDAS) score. RESULTS: There were no differences in baseline characteristics and surgical information between the dexamethasone group and the placebo group. The dexamethasone group had a lower incidence of POD than the placebo group within the first 5 days after surgery [(9/80, 11.3% vs. 21/80, 26.3%, RR = 0.83, 95% CI 0.71-0.97, P = 0.015]. The dexamethasone group had lower MDAS scores (Mean ± SD) than the placebo group [13.2 ± 1.0 (range 11 to 15) vs. 15.48 ± 2.9 (range 9 to 20), P = 0.011, effect size = 0.514]. There were no differences in infection events and hyperglycemia between the two groups. CONCLUSIONS: A single preoperative low-dose dexamethasone may reduce the incidence and severity of POD in geriatric ITF patients with internal fixation surgery. TRIAL REGISTRATION: ChiCTR2200055281.


Asunto(s)
Delirio , Delirio del Despertar , Fracturas de Cadera , Humanos , Anciano , Delirio del Despertar/tratamiento farmacológico , Complicaciones Posoperatorias/epidemiología , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/prevención & control , Estudios Prospectivos , Incidencia , Delirio/epidemiología , Delirio/etiología , Delirio/prevención & control , Fracturas de Cadera/cirugía , Fracturas de Cadera/tratamiento farmacológico , Dexametasona
3.
BMC Musculoskelet Disord ; 24(1): 189, 2023 Mar 13.
Artículo en Inglés | MEDLINE | ID: mdl-36915071

RESUMEN

OBJECTIVE: To design a standardized Tip-Apex Distance (STAD) and analyze the clinical significance of STAD in predicting cut-out in geriatric intertrochanteric fractures with internal fixation. METHODS: Firstly, we designed STAD according to the rule of TAD. We measured the STAD individually based on its own femoral head diameter (iFHD) instead of the known diameter of the lag screw in calculating TAD, resulting in that the STAD is simply the relative quantitation relationship of iFHD (the times of iFHD). In this study, we assumed that all the iFHD was 6D (1iFHD = 6D, or 1D = 1/6 of iFHD) in order for complete match of the Cleveland zone system, easy comparison of the STAD, and convenient identification for artificial intelligence. Secondly, we calculated and recorded all the STAD of cephalic fixator in 123 eligible ITF patients. Thirdly, we grouped all the ITF patients into the Failure and Non-failure groups according to whether cut-out or not, and analyzed the correlation between the cut-out and the STAD. RESULTS: Cleveland zone, Parker's ratio (AP), TAD, and STAD were associated with the cut-out in univariate analysis. However, only STAD was the independent predictor of the cut-out by multivariate analysis. No cut-out was observed when STAD ≤ 2D (1/3 of iFHD). The Receiver Operating Characteristic (ROC) curve indicated that STAD was a reliable predictor of cut-out, and the best cut-off value of STAD was 2.92D. Cut-out rate increased dramatically when STAD increased, especially when STAD > 3D (1/2 of iFHD). CONCLUSION: Essentially, the STAD is a relative quantitation relationship of iFHD. The STAD is a reliable measurement of cephalic fixator position in predicting cut-out in geriatric ITF patients with single-screw cephalomedullary nail fixations. For avoiding cut-out, the STAD should be no more than a half of iFHD. LEVEL OF EVIDENCE: Level III, Prognostic Study.


Asunto(s)
Fijación Intramedular de Fracturas , Fracturas de Cadera , Humanos , Anciano , Cabeza Femoral/diagnóstico por imagen , Cabeza Femoral/cirugía , Fijación Intramedular de Fracturas/métodos , Inteligencia Artificial , Clavos Ortopédicos , Estudios Retrospectivos , Fracturas de Cadera/diagnóstico por imagen , Fracturas de Cadera/cirugía , Resultado del Tratamiento
4.
Front Surg ; 9: 956877, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36329979

RESUMEN

Objective: The aim of this study was to investigate an eccentric distance (ED) zone analysis system for regional evaluation of the cephalic fixator tip based on the ED of the cephalic fixator tip referenced to the radius of its own femoral head to predict cut-out in intertrochanteric fractures (ITF) with internal fixation. Methods: First, we assumed all the femoral heads were regular spheres with the radius (R FD) of "3" for a complete match of the Cleveland zone system and calculated the ED of the cephalic fixator tip by measuring the distances from the cephalic fixator tip to the geometric central axis in the femoral neck and head on both anteroposterior (AP) view and lateral view radiographs. Second, we defined the maximum transverse section of the femoral head into three zones named ED Zone A with ED less than "1," Zone B with ED ranging in "1-2," and Zone C with ED ranging in "2-3" in turns by concentric circles (circles A, B, and C) with the radius of 1/3, 2/3, and 3/3 times of R FD, respectively. Third, we evaluated the ED zones according to the ED and location of the cephalic fixator tip in the eligible 123 ITF patients with single-screw cephalomedullary nail (SCMN) fixation and then analyzed the correlation between the cut-out rate and the ED zones. Results: The cut-out rates in ED Zones A, B, and C were 4.17%, 38.46%, and 100%, respectively. Multivariate logistic regression indicated that ED Zone A had at least a 14 times lower rate of cut-out compared with ED Zone B. The cephalic fixator tip located in ED Zone A has a lower cut-out rate than that in Cleveland Zone 5. The cut-out rate in ED Zone A is significantly lower than that in the region inside Cleveland Zone 5 but outside ED Zone A. Conclusion: ED zone analysis system is a reliable regional evaluation of the cephalic fixator tip position for predicting cut-out in geriatric ITF patients with SCMN fixations and potentially an artificial intelligence measurement during surgery. For decreasing the cut-out rate, the cephalic fixator tip should be located in ED Zone A.

5.
Geriatr Orthop Surg Rehabil ; 13: 21514593221136797, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36310892

RESUMEN

Objective: To report a new surgical position of lateral-tilted supine (LTS) for geriatric proximal humeral fracture operations. Methods: Between January 2016 and December 2020, we adopted the LTS position for operations in 65 geriatric patients with proximal humeral fractures. Results: Sixty-five patients including 25 males and 40 females aged 80.3 ± 8.5 years. The LTS position could be used for almost all proximal humeral fracture surgeries, such as ORIF with plate, suture anchor, and other fixation in 4 patients, open reduction and internal fixation (ORIF) with multiLoc nailing in 48, and shoulder hemiarthroplasty (SHA) in 13. Surgical position setting times were 11.47 ± 2.14 min. The systolic blood pressure changes before and after positioning were 15.07 ± 8.72 mmHg. All of the C-arm X-ray directions, including the cephalic side, contralateral side, and ipsilateral side, can be used in the LTS position surgeries. No surgical complications or no surgical position-related complications were found in these 65 cases. Conclusion: The surgical position of LTS is suitable for geriatric proximal humeral fracture operations.

6.
J Orthop Surg Res ; 17(1): 263, 2022 May 13.
Artículo en Inglés | MEDLINE | ID: mdl-35562761

RESUMEN

BACKGROUND: The location of cephalic fixator tip with different eccentric distance (ED) should have different risks of cutout. This study aims to evaluate the cephalic fixator tip position by measuring ED of the cephalic fixator tip in geriatric ITF patients with single-screw cephalomedullary nail (SCMN) fixation and analyze the correlation between the cutout and the ED. METHODS: Firstly, we assumed all the femoral head was a regular sphere and standardized the radius of the femoral head (RFD) as "3" no matter how big the RFD was for complete match of the Cleveland zone system and convenient identification of artificial intelligence. Secondly, we measured the ED of the cephalic fixator tip by calculating the distances from the cephalic fixator tip to the geometric central axis of the femoral neck and head on both AP view and lateral view radiographs. Thirdly, we evaluated all the ED of the cephalic fixator tip in the eligible 123 geriatric ITF patients and analyzed the correlation between the cutout and the ED. RESULTS: The ED in cutout group (1.25 ± 0.43) is much bigger than that in non-cutout group (0.64 ± 0.34) with significant difference (OR = 50.01, 95% CI 8.42-297.19, p < 0.001). The probability of cutout increased with ED increasing, especially when "ED ≥ 1." The best cutoff value of ED for predicting cutout was "1.022" ("1.022" was just a little bit more than 1/3 times of RFD because "RFD = 3," sensitivity = 73.3%, specificity = 86.1%, and AUC = 0.867, p < 0.001). CONCLUSION: ED is suitable for evaluation of the cephalic fixator tip position for predicting cutout in geriatric ITF patients with SCMN fixation, and ED can potentially be used as artificial intelligence application during surgery. The smaller the ED, the lower the cutout rate. For avoiding cutout, the ED of the cephalic fixator tip should be less than one-third times of the radius of the femoral head.


Asunto(s)
Fijación Intramedular de Fracturas , Fracturas de Cadera , Anciano , Inteligencia Artificial , Clavos Ortopédicos , Fracturas de Cadera/diagnóstico por imagen , Fracturas de Cadera/cirugía , Humanos , Estudios Retrospectivos , Resultado del Tratamiento
7.
Ann Plast Surg ; 87(5): 537-541, 2021 11 01.
Artículo en Inglés | MEDLINE | ID: mdl-34176896

RESUMEN

OBJECTIVE: The aim of the study was to report the clinical outcomes of repair of massive-cavity bone defects after extensive curettage of Campanacci grade II or III giant cell tumor (GCT) around knee with vascularized fibular autograft and cancellous allograft. METHODS: There were 12 consecutive patients with Campanacci grade II or III GCT around knee treated in our department between 2004 and 2016. All the patients underwent clinical evaluation, plain radiography, and/or magnetic resonance imaging of the knee right after admission. To preserve their knee function, we repaired the massive-cavity bone defects after extensive curettage of GCT by vascularized fibular autografts and cancellous allograft. All the patients were evaluated through clinical examinations, plain radiography of the knee and chest, and Musculoskeletal Tumor Society (MSTS) scores of the lower extremity in the follow-ups. RESULTS: The follow-up ranged from 1.5 to 12.0 years (mean, 4.2 years). There were no local recurrences or lung metastasis in any of the 12 patients at the last follow-up. Ten patients had no pain or experienced occasional pain, and 9 were able to resume their previous work. The mean range of motion of knee flexion was 117 degrees, and the extension was -6 degrees. The mean MSTS score was 24.7, and a total of 10 patients had excellent or good MSTS scores. CONCLUSIONS: It is reliable to achieve knee joint salvage and repair massive-cavity bone defects after extensive curettage with vascularized fibular autograft and cancellous allograft in patients with Campanacci grade II or III GCT around the knee.


Asunto(s)
Neoplasias Óseas , Tumor Óseo de Células Gigantes , Aloinjertos , Autoinjertos , Neoplasias Óseas/diagnóstico por imagen , Neoplasias Óseas/cirugía , Trasplante Óseo , Legrado , Estudios de Seguimiento , Tumor Óseo de Células Gigantes/diagnóstico por imagen , Tumor Óseo de Células Gigantes/cirugía , Humanos , Articulación de la Rodilla/diagnóstico por imagen , Articulación de la Rodilla/cirugía , Estudios Retrospectivos , Resultado del Tratamiento
8.
Geriatr Orthop Surg Rehabil ; 12: 2151459321998614, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33717635

RESUMEN

OBJECTIVE: To identify whether the timing of surgery affects red blood cell (RBC) transfusion requirements in the elderly with intertrochanteric fractures. METHODS: We retrospectively studied all patients undergoing surgical fixation of their intertrochanteric fractures in our hospital between January 2009 and December 2018 and analyzed the relationship between the timing of surgery and RBC transfusion. RESULTS: A total of 679 patients were included in this study. The need for RBC transfusion was lower in the patients who underwent surgery within 12 h after admission (timing of surgery <12 h, <12 h group) than those who underwent surgery over 12 h after admission (timing of surgery >12 h, >12 h group) (P = 0.046); lower in the the patients who underwent surgery within 24 h after admission (timing of surgery <24 h, <24 h group) than in those who underwent surgery over 24 h after admission (timing of surgery >24 h, >24 h group) (P = 0.008), and lower in the <24 h group compared to the patients who underwent surgery within 48 h after admission (timing of surgery <48 h, <48 h group) (P = 0.035). Moreover, the need for RBC transfusion was lower in the <24 h group (in the first 24 h from admission to surgery) than in the 24-48 h group (in the second 24 h from admission to surgery) (P = 0.016), and also lower in the <24 h group compared to the 48-72 h group (in the third 24 h from admission to surgery) (P = 0.047). However, there were no differences between the <12 h group and 12-24 h group, between the <12 h group and <24 h group, and between the 12-24 h group and <24 h group, respectively. CONCLUSION: Timing of surgery within 24 h contributes to the reduction of RBC transfusion in the elderly with intertrochanteric fractures.

9.
Ann Plast Surg ; 87(4): 457-460, 2021 10 01.
Artículo en Inglés | MEDLINE | ID: mdl-33512822

RESUMEN

OBJECTIVE: To investigate the clinical outcomes associated with repairing of small-sized wounds of Achilles tendon exposure with proximal pedicled cutaneous neurovascular flap in the dorsolateral foot. METHODS: After thorough debridement, 16 cases with small-sized wounds of Achilles tendon exposure were repaired by proximal pedicled cutaneous neurovascular flap of the dorsolateral foot, and their clinical outcomes were observed. RESULTS: All the flaps in the 16 cases survived completely, excluding the marginal part necrosis in 1 case, and all the wounds were healed. The 2-point discrimination of the flaps was 14.53 ± 1.55 mm (range, 12-17 mm) in patients without sural nerve injury after 3 to 18 months follow-up. No discomfort was felt in wearing normal shoes by all the 16 patients. CONCLUSIONS: It is reasonable to repair the small-sized wounds of Achilles tendon exposure with proximal pedicled cutaneous neurovascular flap of dorsolateral foot due to its effective repair of the wound, relatively uncomplicated surgery, and had satisfactory healing recovery.


Asunto(s)
Tendón Calcáneo , Procedimientos de Cirugía Plástica , Traumatismos de los Tejidos Blandos , Tendón Calcáneo/cirugía , Humanos , Trasplante de Piel , Traumatismos de los Tejidos Blandos/cirugía , Colgajos Quirúrgicos , Resultado del Tratamiento
10.
BMC Musculoskelet Disord ; 17(1): 346, 2016 08 17.
Artículo en Inglés | MEDLINE | ID: mdl-27530935

RESUMEN

BACKGROUND: Giant cell tumors (GCTs) located in the distal radius are likely to recur, and the treatment of such recurrent tumors is very difficult. Here, we report our clinical experience in distal radius reconstruction with vascularized proximal fibular autografts after en-bloc excision of the entire distal radius in 17 patients with recurrent GCT (RGCT) of the distal radius. METHODS: All 17 patients with RGCT in distal radius underwent plain radiography and/or magnetic resonance imaging (MRI) of the distal radius as the initial evaluation after hospitalization. Then the distal radius were replaced by vascularized proximal fibular autografts after en-bloc RGCT resection. We assessed all patients by using clinical examinations, plain radiography of the wrist and chest, and Mayo wrist scores in the follow-ups. RESULTS: After an average follow-up of 4.3 years (range: 1.5-10.0 years), no lung metastasis or local recurrence was detected in any of the 17 patients. In total, 14 patients had excellent or good functional wrist scores, 16 were pain free or had occasional pain, and 15 patients returned to work. The mean range of motion of the wrist was 101° (flexion-extension), and the mean grip strength was 77.2 % of the contralateral normal hand. CONCLUSION: En-bloc excision of the entire distal radius and distal radius reconstruction with a vascularized proximal fibular autograft can effectively achieve local tumor control and preserve wrist function in patients with RGCT of the distal radius.


Asunto(s)
Neoplasias Óseas/cirugía , Trasplante Óseo/métodos , Peroné/trasplante , Tumor Óseo de Células Gigantes/cirugía , Recurrencia Local de Neoplasia/cirugía , Procedimientos de Cirugía Plástica/métodos , Radio (Anatomía)/patología , Adulto , Autoinjertos/irrigación sanguínea , Neoplasias Óseas/patología , Femenino , Estudios de Seguimiento , Tumor Óseo de Células Gigantes/patología , Humanos , Imagen por Resonancia Magnética , Masculino , Persona de Mediana Edad , Radiografía , Radio (Anatomía)/cirugía , Rango del Movimiento Articular , Estudios Retrospectivos , Trasplante Autólogo/métodos , Resultado del Tratamiento , Muñeca/diagnóstico por imagen , Adulto Joven
11.
Plast Reconstr Surg ; 132(5): 784e-789e, 2013 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-24165630

RESUMEN

BACKGROUND: Osteochondromas, especially multiple hereditary osteochondromas, usually cause various deformities of the joints. The authors sometimes find ulnar shortening and acquired wrist varus deformity in distal ulnar osteochondromas and even radial head dislocation resulting in ulnar shortening. In this study, the authors present the clinical outcomes of distal ulnar epiphysis reconstruction in two children using vascularized proximal fibula including the epiphysis after osteochondroma resection. METHODS: The authors used vascularized proximal fibula including the epiphysis as a substitute to reconstruct the distal ulnar epiphysis after osteochondroma resection and investigated the clinical outcome in two patients (aged 4 and 9 years). RESULTS: The wrist deformity was corrected successfully for both cases. Bone union between fibular grafts and hosts was found 2 months postoperatively. The reconstructed distal ulna and contralateral limbs were growing almost simultaneously. The morphology and function were also satisfactory at 1- and 8-year follow-up, respectively. CONCLUSIONS: It is possible to reconstruct the distal ulna after osteochondroma resection and simultaneously keep the ulna in longitudinal growth by using vascularized proximal fibula including the epiphysis in children. However, the growth plate in the reconstructed distal ulnar epiphysis might be prematurely closed approximately 8 years after reconstruction. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, V.


Asunto(s)
Neoplasias Óseas/cirugía , Epífisis/cirugía , Peroné/trasplante , Osteocondroma/cirugía , Procedimientos de Cirugía Plástica/métodos , Cúbito/cirugía , Niño , Preescolar , Epífisis/trasplante , Femenino , Humanos , Masculino , Estudios Retrospectivos , Muñeca/cirugía
12.
J Reconstr Microsurg ; 29(9): 593-600, 2013 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-23804020

RESUMEN

Posttraumatic infected massive bone defects in lower extremities are difficult to repair because they frequently exhibit massive bone and/or soft tissue defects, serious bone infection, and excessive scar proliferation. This study aimed to determine whether these defects could be classified and repaired at a single stage. A total of 51 cases of posttraumatic infected massive bone defect in lower extremity were included in this study. They were classified into four types on the basis of the conditions of the bone defects, soft tissue defects, and injured limb length, including Type A (without soft tissue defects), Type B (with soft tissue defects of 10 × 20 cm or less), Type C (with soft tissue defects of 10 × 20 cm or more), and Type D (with the limb shortening of 3 cm or more). Four types of single-stage microsurgical repair protocols were planned accordingly and implemented respectively. These protocols included the following: Protocol A, where vascularized fibular graft was implemented for Type A; Protocol B, where vascularized fibular osteoseptocutaneous graft was implemented for Type B; Protocol C, where vascularized fibular graft and anterior lateral thigh flap were used for Type C; and Protocol D, where limb lengthening and Protocols A, B, or C were used for Type D. There were 12, 33, 4, and 2 cases of Types A, B, C, and D, respectively, according to this classification. During the surgery, three cases of planned Protocol B had to be shifted into Protocol C; however, all microsurgical repairs were completed. With reference to Johner-Wruhs evaluation method, the total percentage of excellent and good results was 82.35% after 6 to 41 months of follow-up. It was concluded that posttraumatic massive bone defects could be accurately classified into four types on the basis of the conditions of bone defects, soft tissue coverage, and injured limb length, and successfully repaired with the single-stage repair protocols after thorough debridement.


Asunto(s)
Alargamiento Óseo , Fracturas Óseas/cirugía , Traumatismos de la Pierna/clasificación , Traumatismos de la Pierna/cirugía , Microcirugia/métodos , Colgajos Quirúrgicos , Adolescente , Adulto , Niño , Desbridamiento , Femenino , Peroné/trasplante , Fracturas Óseas/complicaciones , Humanos , Traumatismos de la Pierna/complicaciones , Masculino , Persona de Mediana Edad , Traumatismos de los Tejidos Blandos/cirugía , Adulto Joven
13.
Spine (Phila Pa 1976) ; 37(17): 1463-9, 2012 Aug 01.
Artículo en Inglés | MEDLINE | ID: mdl-22842538

RESUMEN

STUDY DESIGN: Retrospective multicenter study. OBJECTIVE: To compare clinical outcomes and surgical-related adverse events in patients with multilevel cervical myelopathy (MCM) undergoing simple anterior, simple posterior, or 1-stage posterior-anterior surgical decompression strategies. SUMMARY OF BACKGROUND DATA: Simple anterior, simple posterior, and 1-stage posterior-anterior surgical decompression strategies have been advocated for MCM treatment in both Western and Chinese populations. However, there is limited evidence on whether 1-stage posterior-anterior strategy may offer equal or more advantages than the other 2 strategies for patients with MCM. METHODS: A retrospective review of medical records was conducted for 255 patients with MCM who had undergone surgical decompression in 3 Chinese spinal centers from 1999 to 2010. Neurological status, perioperative variables, and surgical complications were assessed. Multiple linear regression was used to evaluate factors associated with the outcomes of each strategy. RESULTS: Analyses were conducted on a total of 229 patients with MCM undergoing surgical decompression via 1-stage posterior-anterior (68 patients), simple anterior (102 patients), and simple posterior approaches (59 patients). One-stage posterior-anterior approach had the highest Japanese Orthopaedic Association recovery rate after adjusted for age and sex (adjusted mean ± SD: 50.0 ± 3.2, P < 0.001) and additionally adjusted for smoking, duration from onset of symptoms to surgery, comorbidities, preoperative Japanese Orthopaedic Association score, Ishihara's curvature index and Pavlov ratio, operative blood loss, operating time, anterior operated disc levels, and posterior operated levels (adjusted mean ± SD: 51.6 ± 11.6, P < 0.01). Anterior approach had the largest difference between the pre- and postoperative Ishihara's curvature indexes after adjusted for age and sex (adjusted mean ± SD: 5.3 ± 1.0, P < 0.01) and after multivariable adjustment (adjusted mean ± SD: 6.5 ± 2.8, P = 0.003). CONCLUSION: One-stage posterior-anterior strategy can be a reliable and effective treatment strategy for MCM in a subgroup of patients with anterior and posterior compression on spinal cord simultaneously.


Asunto(s)
Descompresión Quirúrgica/métodos , Enfermedades de la Médula Espinal/cirugía , Médula Espinal/cirugía , Adulto , Anciano , Obstrucción de las Vías Aéreas/etiología , Pueblo Asiatico , Vértebras Cervicales , China , Descompresión Quirúrgica/efectos adversos , Femenino , Humanos , Infecciones/etiología , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias/etiología , Recuperación de la Función , Estudios Retrospectivos , Médula Espinal/patología , Médula Espinal/fisiopatología , Compresión de la Médula Espinal/etnología , Compresión de la Médula Espinal/fisiopatología , Compresión de la Médula Espinal/cirugía , Enfermedades de la Médula Espinal/etnología , Enfermedades de la Médula Espinal/fisiopatología , Resultado del Tratamiento
14.
J Reconstr Microsurg ; 26(2): 109-15, 2010 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-20013588

RESUMEN

We report the clinical outcomes of homeochronous usage of massive bone allografts with vascularized fibular autografts for the biological repair of lower-extremity bone defects secondary to bone tumor excision. Large bone defects in the lower extremities of 17 patients (10 men and seven women; age range, 6 to 34 years) who underwent bone tumor excision were repaired using massive bone allografts along with vascularized fibular autografts. After 6 to 48 months (mean, 20.2 months) of follow-up, the wounds at the donor and recipient sites healed in one stage, the monitoring flaps remained viable, the immune response to the massive bone allografts was minimal, and there were no complications in the donor limbs. Of the 17 patients, 13 and 3 cases showed radiographic union in 6 months and 8 months after surgery, respectively; one case of malignant synovioma showed recurrence, and therefore, leg amputation was performed 2.5 months after surgery. None of the massive bone allografts were absorbed or fractured at the last follow-up. The Mankin evaluation rating was excellent in eight cases, good in five cases, fair in two cases, and poor in two cases; the total rate of excellent and good cases was 76.47%. Homeochronous usage of massive bone allografts with vascularized fibular autografts is a satisfactory method for the biological repair of massive bone defects in the lower limbs after bone tumor excision.


Asunto(s)
Neoplasias Óseas/cirugía , Neoplasias Femorales/cirugía , Peroné/trasplante , Colgajos Quirúrgicos/irrigación sanguínea , Tibia/cirugía , Adolescente , Adulto , Neoplasias Óseas/diagnóstico por imagen , Neoplasias Óseas/patología , Niño , Femenino , Neoplasias Femorales/diagnóstico por imagen , Neoplasias Femorales/patología , Peroné/irrigación sanguínea , Peroné/diagnóstico por imagen , Estudios de Seguimiento , Humanos , Fijadores Internos , Masculino , Radiografía , Tibia/diagnóstico por imagen , Tibia/patología , Trasplante Autólogo , Trasplante Homólogo , Resultado del Tratamiento , Cicatrización de Heridas
15.
Chin J Traumatol ; 8(6): 375-8, 2005 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-16313716

RESUMEN

OBJECTIVE: To evaluate operative effects of a new method to reconstruct anterior crucial ligament (ACL) and posterior crucial ligament (PCL) simultaneously by using patellar tendon under arthroscopy. METHODS: From November 1999 to November 2003, the injured ACL and PCL of 11 patients were fixated with compressed screws and reconstructed under arthroscopy with the bone-patellar tendon-bone treated with deep hypothermia andgamma radiation. At the same time, 2 patients were treated with medial collateral ligament (MCL) reconstruction, 3 with lateral collateral ligament (LCL) reconstruction, 1 with meniscus suture and 4 with whole or partial resection. RESULTS: All patients were followed up for 12-26 months (average 16.5 months). The Lysholm score method was employed to evaluate the knee function. The average preoperative score was 45.3 and the postoperative score was 86.4. Anterior drawer test (ADT) was positive in 11 knees preoperatively and feeble positive in one knee postoperatively. Lachman test was positive in 11 knees preoperatively and in one postoperatively, and feebly positive in two postoperatively. Posterior drawer test was positive in 11 knees preoperatively and feebly positive in 2 postoperatively. There were 2 knees with tolerable pain and 2 with knee flexion of 5-20. CONCLUSIONS: As for simultaneous reconstruction of ACL and PCL under arthroscopy, allogeneic bone-patellar tendon-bone can not only avoid injury and complication caused by autografting, but also help rehabilitation of the knee function.

16.
Chin J Traumatol ; 8(2): 81-5, 2005 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-15769305

RESUMEN

OBJECTIVE: To explore a treatment approach for severely injured lower extremities. METHODS: The data of 42 patients with severely traumatic lower extremities from 1989 to 1999 were retrospectively reviewed. According to MESS (mangled extremity severity score) the mean score of all the limbs was 6.24+/-1.45, 34 cases had MESS score < 7 and 8 cases had MESS score > or = 7. Treatment approaches included microvascular anastomosis technique, compound tissue flap transplantation technique and compound bone tissue flap transplantation. RESULTS: Two patients died after operation and one patient had delayed amputation of a lower limb. The rest 39 patients were followed up for 4-13 years. All the lower extremities of the 39 patients survived and had equal length. The 39 cases were evaluated by Chen's criterion, showing that 37 had good result (29, Chen I and 8, Chen II), 1 sufficient (Chen III) and 1 poor (Chen IV). CONCLUSIONS: Successful emergency treatment of severely injured lower extremities could be achieved by using microsurgery techniques and strict controlling of lower extremity salvagel indications.


Asunto(s)
Medicina de Emergencia/métodos , Traumatismos de la Pierna/terapia , Procedimientos Ortopédicos/métodos , Adolescente , Adulto , Niño , Femenino , Estudios de Seguimiento , Fracturas Óseas/fisiopatología , Fracturas Óseas/terapia , Humanos , Traumatismos de la Pierna/fisiopatología , Masculino , Persona de Mediana Edad , Traumatismo Múltiple/fisiopatología , Traumatismo Múltiple/terapia , Músculo Esquelético/fisiopatología , Rango del Movimiento Articular , Recuperación de la Función , Estudios Retrospectivos , Análisis de Supervivencia , Trasplante de Tejidos/métodos , Resultado del Tratamiento
17.
Chin J Traumatol ; 6(5): 275-9, 2003 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-14514363

RESUMEN

OBJECTIVE: To study the effect of vascularized fibular graft on large defects of long bones and the monitoring method for the vascular status of the grafted fibula. METHODS: From March 1988 to February 1998, 30 patients with long bone defects over 6 cm in length received vascularized fibular graft including a monitoring island flap in our department to monitor the blood circulation of the fibulae. RESULTS: Monitoring island abnormalities were indicated in 6 flaps, which accurately gave the alarm of the circulation crisis of the fibular graft. Surgical exploration was performed timely and the blood supply was recovered instantaneously. All the bone defects were healed at 6 months postoperatively. After 4 years of follow-up, all the grafted fibulae were thickened and were just like tibiae. CONCLUSIONS: A monitoring island flap is a satisfactory method for repairing large defects of the long bones and a reliable method for assessing the vascular status of the grafted fibulae.


Asunto(s)
Trasplante Óseo/métodos , Peroné/trasplante , Colgajos Quirúrgicos , Adolescente , Adulto , Anastomosis Quirúrgica , Niño , Preescolar , Femenino , Peroné/irrigación sanguínea , Humanos , Masculino , Persona de Mediana Edad , Resultado del Tratamiento , Cicatrización de Heridas
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